On the benefits and role of electron-induced dissociation in lipidomics
NOTE: After the initial publication of this post, we added more details and results on the correct (!) annotation of lipids with multiple double bonds. It's at the end.One of the grand challenges in metabolomics using mass spectrometry (MS) is the limited and somewhat redundant information provided by collision-induced dissociation (CID). CID is incredibly versatile and quick but tends to fragment weaker bonds, such…